Medical research has been defined as Trials that evaluate an investigational drug, biological, or medical device on patients at a rigorously, clinically controlled setting to be able to check the efficacy and safety of an experimental thing. Medical research involves use of people in experiments. As medical research involves human participants there is a possibility of them becoming exploited in the name of science, hence sponsors and researchers are legally and ethically obligated to protect them. In Clinical practice a doctors use interventions which are made to cure a disease and with the sole goal of enhancing the wellbeing of a person.
However research is intended to check its effectiveness, a new medicine, to answer questions about ailments health and it heals. Here, the player in a clinical trial may not get the duty of investigator towards the topic and so the treatment. The Now, declaration of Helsinki by World Medical Assembly forms the cornerstone of guidelines for research. It entails 32 principles and informed consent is a vital requirement for ethical conduct of a clinical trial. In addition, the statement clearly specifies that all protocols must be submitted to an ethics committee for inspection, which has to be independent of the investigator, the sponsor or any other kind of undue influence.
The bashir dawood Ethical Guidelines for Biomedical Research on Human subjects expects that all institutions in India which execute any kind of research involving human beings ought to follow the guidelines to safeguard the security and wellbeing of all subjects. Any trial must be carried out from an ethics committee with consent. It could experimental research involving a new drug or new device or a simple questionnaire-based study, in normal subjects or in patients, so long as it involves individuals, the investigator should obtain ethics committee consent. Papers must conform to these guidelines if the trial must be acceptable. The Principles to research and application of values is integrity. There are hardly any arguments against the requirement of review of protocols before beginning the research.